6 Kratom Potentiators Proven to Work (#1 Is A Secret)

What are the best kratom potentiators that can enhance the power of mitragyna speciosa? That’s the question we’ll tackle today.

You can enhance and make kratom stronger. Improve the relaxation effects and camouflage the bitter taste. 

The first supplement I’ll talk about is GABA brainfood. This one is my top favorite way to potentiate kratom. The second one is good if you use kratom to kill pain.  You will also notice that kratom tends to get excited with spices.

GABA BrainFood Supplement

kratom potentiators

This supplement is designed to enhance and maintain healthy brain function. I noticed it works well with kratom.

To understand how you can use this to spark up kratom I’ll explain how it works.

GABA (Gamma-Aminobutyric Acid) is produced by your system naturally.  It is a neurotransmitter, a brain chemical crucial for mental calmness. It slows down brain activity so you can have more fluid thoughts and relax.

This supplement is also infused with three ingredients:

  • L-Citrulline
  • Rosmarinic Acid
  • Grape Seed Extract


This amino acid is found in foods like watermelon, beef, and pork. L-Citrulline helps to transport GABA to your brain.

Kratom itself acts on GABA receptors in your brain so this supplement alone is good.

Rosmarinic Acid

Found in natural herbs like rosemary. It slows down the breakdown of GABA, which makes the calming effects kratom produce last longer. Rosmarinic Acid alone promotes relaxation.

Grape Seed Extract

Works similar to L-Citrulline. Grape seed extract helps GABA to cross the blood-brain-barrier and transport it further to your brain.

Why BrainFood?

Only take this supplement if you want to potentiate kratom and the relaxing effects. You’ll feel a sense of serenity. At night you can drift into a deep and well-earned restful sleep.

Kratom itself acts on the neurotransmitter GABA. This supplement will work together with kratom to produce stronger and unique experiences. A true potentiator.


Agmatine is a metabolite of an essential amino acid called L-arginine. It works in synergy with opioids to reduce pain. Agmatine has also shown to minimize the risk to become addicted to opioid and even preventing tolerance.

Agmatine can release some opioids by stimulating the adrenal glands. The release of β-endorphin is released, which is a naturally produced opioidergic painkiller.

You should try agmatine if you want to enhance and solely use kratom for pain relief.

Akuamma Seed

Akuamma has a lot in common with kratom. Both comes from a tropical tree, has a bitter taste, and are structurally related.

The kratom alkaloids and akuamma will produce stronger effects that for some last a long time. Some people who tried it say it’s the best potentiators while others can’t stand the taste.



This article won’t be complete if I didn’t include grapefruit. Why? Grapefruit stimulates the metabolism of kratom. More active alkaloids in your system are now stronger and stay in your system longer. Grapefruit also improves the taste.

I use grapefruit to improve the kratom experience. Both taste and potency are enhanced, what else can I ask for?  You can use one fruit and blend using a mixer. When you finish let it sit for 10 minutes so the juice has time to do the work on the plant.



Turmeric, a polyphenol with great health benefits and a reliable kratom potentiator that can enhance the effects and make them last longer. It works great even if you’ve developed a tolerance to kratom. I suggest using premade turmeric shots or a potent extract.

Besides a stronger kratom, turmeric can also decrease inflammation and general pain, which makes it a  good source of additional pain management to add into the mix.

Cayenne Pepper

Found in many spicy meals, cayenne pepper can enhance your kratom experience. You need to be mindful of doses because it can build up a tolerance.

Cayenne Pepper has high levels of capsaicin which offers you some pain relief.

Mix the pepper and kratom with water and feel the difference. Some people take Turmeric also to spice up the mix, but if it’s your first time potentiating kratom try one at the time.

Spicy food and snacks seem to work well as kratom potentiators.

Lemon Balm

lemon balm

A popular mild sedating herb, Lemon Balm works well to calm down brain activity so it gets easier to drift into a restful sleep. It works well on its own but with kratom, the sedating effects are empowered.

Good to add relaxation to the mix


CBD oil

CBD is the non-psychoactive ingredient in the cannabis plant. Kratom and CBD from cannabis are both god-sent herbs that you can use for many health benefits. Pain management, fibromyalgia, depression, and anxiety to name a few. CBD does its magic to stimulate and balance your endocannabinoid system, which regulates physiological and cognitive processes, including pain and mood.

You using CBD to potentiate kratom is something you won’t regret anytime soon. Just like kratom, CBD is booming online.

CBD is good for pain and it deserves everyone’s attention if they are using kratom for dealing with pain.

Improve The Breakdown of Kratom

digestive system

Digestion is basically the process of breaking down food into smaller molecules that your body can use. When you take kratom your body won’t necessarily utilize it 100% if your digestive system isn’t operating on a superhuman level.

You can improve your digestion with two supplements:


Pancreatin is a supplements mixture of enzymes used to break down food. This supplement is recommended to treat a bad digestive system, malabsorption.

Papaya Enzymes

This tasty fruit is filled with enzymes to help digestion and stabilize blood sugar levels. Papaya enzymes is a good source of enzymes to take with food because some enzymes diminish during cooking.


Ever since kratom became available online people have tried and experimented to enhance its power. These are my favorite kratom potentiators that work well. Grapefruit and turmeric are my absolute favorite.

Try different ones from this list and you’ll eventually find the one your body likes. Some kratom potentiators, such as cayenne pepper, turmeric, and grapefruit seems to work for most people. 

If you want to boost kratoms pain relief you should try agmatine.

How do you potentiate your kratom? Add a comment and teach me.


Agmatine – Scientific Review

Cannabinoids in the management of difficult to treat pain