How Niacin for Depression Can Restore Your Happiness Chemicals

Never thought I use niacin for depression when I saw  it for the first time on the nutrition value on my Noccoo can, but I’m glad I did.

Niacin is another word for nicotinic acid and Vitamin B3. It comes in two forms: nicotinamide and inositol Hexa-nicotinate. Both are effective to treat depression.

All vitamin B’s are crucial for brain and body function.

They help your body to convert food into fuel.

They keep your skin, hair, liver, and eyes healthy.

In this article, you’ll learn how to use niacin for depression.

Niacin Deficiency Symptoms:

  • Depression
  • Poor blood circulation
  • Vomiting
  • Canker sores
  • Fatigue
  • Indigestion
  • Low motivation

Why is Niacin Good for Depression?

No explanation exists on how niacin damps down depressive symptoms, neither do you need any.

Here’s why.

Your body can’t store vitamin b’s.

Because they are water soluble. Take enough niacin every day is therefore important if you feel depressed. 

Niacin & Serotonin

Serotonin. Have you ever heard of it before?

I bet you have!

It’s a major brain chemical that handles appetite, sleep, mood, and many other physiological functions.

Tryptophan, an essential amino acid, is a major building block of serotonin. And niacin is one of the building blocks of tryptophan. If you take these two together you got a powerful weapon to fight depression.

Niacin & Your Nervous System

Niacin makes sure that all the cells in your body to function properly.

When your nervous system is running smooth, symptoms such as anxiety, mood swings, insomnia, and depression can be avoided and damped down.

You’ll feel so much better when you take all the vitamin b’s.

Do you have a b-complex bottle at home?

You should, or at least, in this case, have a niacin bottle. Because it allows you to get the most out of the other treatments you have for depression.

How Much Niacin for Depression?

You can buy niacin pills with 50, 100, or 250mg in each one.

How much you should take depends on your individual self. And if you’re doing the ”niacin flush”, which you’ll learn about soon.

Some people take 1g each day. I take 500mg, which has worked fine for me. There are even people who take 7000mg. But you probably won’t need that much.

What Kind of Niacin for Depression?

Good question!

There are two types of niacin: nicotinic acid and nicotinamide, which is the flush-free form.

For depression, you should go with the flush type.

I have both because you should not flush every day.

niacin for depression

Understanding The Niacin Flush & My Experience

Niacin makes the small blood vessels in your skin dilate. More blood can, therefore, flow through and you’ll feel a burning sensation and your face turns red.

When the flush has passed it will also flush away toxic waste and make your skin look healthy and fresh.

I took 100mg niacin with a glass of water in the morning on an empty stomach. 20-30 minutes later, my face turned red and I got this burning sensation. 15 minutes later the flush began to wear off and I noticed a huge burst of energy and happiness.

However, everyone will have their own experience. A niacin flush can last for ten minutes up to two hours.

Your body starts to adjust to a specific dose over time. 100mg might not work well for me after a month. So I need to perhaps take 150 or 250mg to induce a flush.

It is recommended to take niacin with a meal after you’ve had your breakfast.

The flush is uncomfortable, but it will pass and it’s harmless. Drink extra filtered water to reduce the sensations.


If you want to use niacin for depression you should use the nicotinic acid type. Start with 100mg after you have a breakfast and wait for the sensations.

When you don’t feel anything anymore it means your body has adjusted, so you need to increase the dose to 150mg.

You should also get the flush-free type of niacin because you aren’t going to flush every day? Both are good for depression. But flushing is more powerful.

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