A small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme highly expressed in adipose tissue.

Rodent studies report reduced fat mass without changes in food intake. Human data is thin. Chemically a small molecule, not a peptide.

A modified fragment of the C-terminus of human growth hormone, studied for stimulating fat breakdown.

Investigated in obesity and fat-metabolism models. Rodent data is strongest; human results underwhelming.

Derived from the helix B region of erythropoietin. Binds the innate repair receptor rather than the classical EPO receptor.

Investigated in small fiber neuropathy and neuropathic pain research, including sarcoidosis and diabetic neuropathy.

Dissipates the mitochondrial proton gradient, causing cells to burn more fuel to maintain ATP production.

Studied in metabolic rate and fat oxidation research. A newer generation of mitochondrial uncouplers.

Researched for its role in angiogenesis (new blood vessel formation) and cytoprotection across multiple tissue types.

The most-studied healing peptide. Investigated in tendon, ligament, muscle, and gut-lining repair models. Frequently paired with TB-500.

Induces tyrosine hydroxylase and AAAD, the rate-limiting enzymes in dopamine and serotonin biosynthesis.

Studied as an 'actoprotector' — enhancing physical and mental performance without stimulant crash.

A modified version of amylin, the hormone co-secreted with insulin. Researched for slowing gastric emptying.

Most studied in combination with semaglutide (CagriSema), where pathways produce additive effects.

A short peptide from the Khavinson family targeting myocardial tissue gene expression and mitochondrial function.

Part of the organ-specific bioregulator series. Most evidence from Russian research groups.

A two-amino-acid peptide targeting cartilage tissue gene expression and extracellular matrix maintenance.

Part of the organ-specific bioregulator series.

A short peptide targeting cerebral cortex gene expression and cognitive function.

Studied alongside Pinealon in neural aging research, though Chonluten targets cortical rather than pineal tissue.

A modified GHRH peptide researched for extending the body's own growth-hormone-releasing signal.

Commonly studied with Ipamorelin. The no-DAC version is preferred for pulsatile pattern.

CJC-1295 with a Drug Affinity Complex (DAC) attached, producing sustained rather than pulsatile GH elevation.

Studied for extended pharmacokinetic profile. Some researchers prefer the no-DAC version for physiological pulsatile signalling.

A short peptide targeting adrenal cortex tissue gene expression.

Part of the organ-specific bioregulator series.

An angiotensin IV analog researched for promoting synaptogenesis (new synaptic connections).

Studied in neuroplasticity and memory research. In vitro potency reported orders of magnitude higher than BDNF; in vivo translation remains the open question.

A naturally occurring nonapeptide researched for promoting deep sleep and modulating stress-response pathways.

Investigated in sleep-regulation and stress-response research. Also studied for opioid-receptor modulation.

A synthetic tetrapeptide researched for stimulating telomerase activity and melatonin rhythm regulation.

A cornerstone of longevity peptide research. Khavinson's group reports telomere lengthening in aged animal models.

A high-affinity binding protein that prevents myostatin (GDF-8) and related ligands from engaging their receptors. See the Follistatin-344 buyer and purity guide for isoform, CAS and third-party testing criteria.

Used as a research tool for myostatin pathways, TGF-β superfamily biology, and ligand-receptor dynamics.

Disrupts the FOXO4-to-p53 interaction inside senescent cells while leaving healthy cells alone.

2017 rodent work reported restored fur density, kidney function and fitness in aged mice. No human evidence yet.

Combines a CKGGRAKDC homing motif with a (KLAKLAK)2 proapoptotic domain that disrupts mitochondrial membranes after uptake.

Studied as a model for tissue-selective peptide delivery and adipose vasculature remodelling.

Researched for stimulating collagen and glycosaminoglycan synthesis in skin and wound repair.

Widely studied in dermatological and anti-aging research. One of the few peptides with substantial human skin data.

A ghrelin receptor agonist researched for triggering a large growth hormone pulse.

One of the older secretagogues. Known to be a compound counterfeiters have shipped in mislabelled vials.

A ghrelin receptor agonist with strong hunger signalling, the most reported feature versus ipamorelin.

Studied in growth hormone research and in appetite and gastric motility models.

Found in every cell; functions as the primary endogenous antioxidant and supports Phase II detoxification.

One of the most studied molecules in biochemistry. The research question is bioavailability of supplemental forms.

A GnRH agonist with D-Trp6 substitution increasing receptor affinity.

Studied in reproductive endocrinology and hormone-dependent tissue research.

Binds GnRH receptors on pituitary gonadotrophs, stimulating FSH and LH release.

Studied in reproductive endocrinology and as a diagnostic tool for pituitary function.

A glycoprotein hormone researched for Leydig cell function and endogenous testosterone signalling.

One of the better characterised compounds due to its long clinical history in fertility research.

A synthetic hexapeptide. Unlike other GHRPs, also interacts with CD36, a scavenger receptor for lipid sensing.

Used as a reference compound in GHS-R1a pharmacology. Dual receptor profile makes it unique for studying lipid-metabolism pathways.

Research examines whether this region carries lipolytic activity while leaving glucose effects behind.

AOD-9604 is a modified version of this same fragment. Rodent data is strongest.

Contains both FSH and LH bioactivity, activating Gsα-coupled cAMP/PKA signalling via FSHR and LHCGR.

Used in gonadotropin receptor pharmacology and glycoprotein hormone structure-function studies.

The truncation increases local bioavailability at the tissue level.

Studied alongside IGF-1 LR3. Shorter half-life but potentially more active locally.

Has an arginine substitution and 13-amino-acid N-terminal extension reducing IGFBP binding.

Studied in muscle-growth and tissue research. Binds IGF-1 receptors with higher affinity.

Researched for stimulating a pulse of growth hormone release with minimal appetite or cortisol effect.

Often paired with CJC-1295. One of the most popular research peptides in the GH axis category.

A KISS1 gene product that signals to GnRH neurons via the GPR54 receptor.

Studied in fertility, reproductive endocrinology, and in imaging work on sexual and emotional processing.

A tripeptide fragment of alpha-MSH researched for action in gut and skin inflammation models.

Studied alongside BPC-157 in gut and inflammation research.

A short peptide targeting vascular tissue gene expression.

Part of the organ-specific bioregulator series.

A 37-amino-acid antimicrobial peptide researched for direct antimicrobial action and biofilm disruption.

Studied in chronic wound, biofilm and innate immunity research. Pro-inflammatory in some models.

Researched for stimulating eumelanin production via MC1R with fewer off-target effects than MT-II.

The best clinically documented melanocortin compound, studied in erythropoietic protoporphyria.

Researched for stimulating melanin production and arousal effects.

Studied in pigmentation research; libido effects noted as secondary. Less selective than Melanotan I.

A splice variant of IGF-1 studied for satellite cell activation in early muscle repair.

Studied in muscle regeneration research. Available as native MGF and PEG-MGF.

Researched for metabolic regulation, insulin sensitivity, and AMPK activation.

Studied in metabolic and exercise-performance research. Represents the field of mitochondrial genomics.

Research examines whether blocking GDF-8 promotes hypertrophy through Smad2/3 inhibition.

Studied in muscle-wasting and sarcopenia models.

Levels decline with age; research examines whether supplementation restores metabolic and repair capacity.

Heavily studied and genuinely contested. The open question is how much intact NAD+ reaches cells.

Researched for NGF, BDNF, and AMPA/NMDA receptor modulation.

One of the most widely used nootropic peptides.

Identified through screening ~10,000 compounds for neural stem cell proliferation.

Studied in neurogenesis and mood research. Distinct from all peptide-based cognitive compounds.

Development code LY3502970. Engages the GLP-1 receptor through a non-peptide scaffold.

Studied for GLP-1R binding kinetics and cAMP-pathway activation. Next generation of GLP-1 compounds.

A two-amino-acid peptide targeting liver tissue.

Part of the organ-specific bioregulator series.

Produced in the hypothalamus and released by the posterior pituitary.

One of the most studied neuropeptides in psychology, though the intranasal literature has a replication problem.

CNTF fragment with structural modifications for proteolytic stability and BBB permeability.

Studied within the neurotrophic factor signalling framework.

A short peptide targeting pancreatic tissue.

Part of the organ-specific bioregulator series.

Derived from the sortilin propeptide.

Rodent work reports antidepressant-like effects within days rather than weeks. No human trials.

PEGylation protects the peptide from rapid enzymatic degradation.

Studied as the longer-lasting version of MGF for muscle regeneration.

A short peptide researched for influencing gene expression in neural tissue.

Most evidence comes from Russian research groups over several decades.

A peptide targeting prostate-specific gene expression.

Part of the organ-specific bioregulator series.

Researched for sexual arousal through CNS pathways rather than the vascular system.

Has FDA approval under the brand name Vyleesi for a specific indication.

A triple-receptor agonist.

One of the newest metabolic research peptides. Early research reports larger effects than dual agonists.

Researched for anxiolytic effects via GABA, BDNF, and enkephalin-degradation-inhibition pathways.

Frequently paired with Semax for combined calm-and-focus research.

Researched for appetite regulation, blood-sugar handling, and slowed gastric emptying.

Among the most clinically researched compounds in the metabolic space.

Researched for effects on BDNF, NGF, and cognitive function via melanocortin pathways.

Studied in cognition and neuroprotection research.

A 29-amino-acid GHRH fragment researched for stimulating pituitary growth hormone production.

One of the longest-studied GH-releasing peptides.

A synthetic pan-agonist of estrogen-related receptors that regulate mitochondrial gene programs.

Rodent studies report increased mitochondrial function and endurance. No human data.

Improves electron transport chain efficiency by preserving cristae structure.

One of the few compounds here with real clinical trial data, studied in mitochondrial myopathy and heart failure.

Studied for actin-binding and promoting cell migration in tissue repair.

Frequently paired with BPC-157 (the 'Wolverine Stack') to cover complementary healing pathways.

A stabilized GHRH analog studied for its effect on growth hormone and visceral adipose tissue.

The most clinically investigated GH-axis peptide, notably in HIV-associated lipodystrophy.

Inhibits reuptake of all three monoamines simultaneously.

Studied in obesity research models. Triple mechanism distinguishes it from single-pathway suppressants.

A two-amino-acid peptide targeting testicular tissue.

Part of the organ-specific bioregulator series.

A two-amino-acid peptide targeting thymic tissue.

Studied alongside Vilon in thymic bioregulation research.

Naturally produced by the thymus.

Among the more clinically studied immune-modulating peptides. Studied in hepatitis and vaccine adjuvant research.

A nonapeptide secreted by thymic epithelial cells.

Studied in immune aging research. Thymulin levels fall sharply as the thymus involutes with age.

A dual-receptor agonist researched for combined GLP-1 and GIP activity.

Studied for stronger metabolic effects than single-pathway GLP-1 compounds.

A two-amino-acid peptide from the Khavinson family.

Rodent lifespan studies report extended median lifespan. Independent replication outside Russia limited.

A signalling peptide found across the gut, lungs and nervous system.

Studied in autoimmune and chronic inflammatory research. Appears in mold/CIRS protocols.