Top Bioregulator Peptides: 26 Organ-Specific Compounds & What They Do

Bioregulator peptides have 50+ years of research behind. More than 15 million patients have used them.

There are two types:

• Natural bioregulators (Cytomaxes): Extracted from animal organs. Gradual onset with 4 to 6 months of lasting effects.
• Synthetic bioregulators (Cytogens): Lab-made. Faster action with 1.5 to 2 months of lasting effects.

Most researchers combine synthetic for initiation and natural for maintenance.

Epitalon

One of the most researched bioregulator peptides that target the pineal gland.

A 2025 study shows that it can lengthen telomeres (the protective caps on your DNA) through two specific pathways. No other peptide can do both.

Treated cells can divide 10 times as often as normal cells, increasing their longevity by approximately 30%.

A study of 266 elderly people who took Epitalon yearly for 6 years found 4x lower mortality than the control group.

Researchers Report:

• Better sleep
• Even energy
• Faster recovery
• Feeling more in tune throughout the day

Epitalon has been shown to influence the pineal gland’s production of melatonin. Helps restore the natural circadian rhythm of neurotransmitters like norepinephrine and dopamine.

Thymalin

Targets the thymus gland, which produces your immune cells.

The thymus shrinks as we age and becomes mostly fat by 50.

A COVID-19 trial found faster recovery with better immune markers in patients.

When taken with Epitalon, it has been shown to prolong the active longevity for people over 60.

Researchers Report:

• Getting sick less often
• Faster recovery
• Feeling more resilient

Clinical Update: The recent clinical assessment of COVID-19 patients who received Thymalin in addition to standard therapy showed a significantly slower decline in IgG antibodies, with levels remaining 32% higher than control levels at 100 days. It also aided normalization of blood parameters associated with the “cytokine storm” and of respiratory function.

Vilon

The smallest bioregulator with just two amino acids. Works by uncompressing DNA to make genes readable again.

It has been shown to inhibit tumor growth by over 60% in animal studies.

Researchers Report:

• Better immune function
• General sense of vitality

Pinealon

Protects neurons from damage. Research shows it can prevent breakdown of brain cells in Alzheimer’s and Huntington’s models.

In one study, 72 people with traumatic brain injuries showed improved memory.

Researchers Report:

• Sharper memory
• Clearer thinking
• Enhanced focus
• Less brain-fog

Cerluten

Extracted from brain tissue. Supports neuron communication. Contains multiple peptide types rather than just one.

Researchers Report:

• Brain fog dissolves within 1-2 weeks
• Improved concentration abilities
• More cognitive endurance during long work sessions

Cortagen

A synthetic brain peptide that affects gene expression to help nerve recovery after injury and unlock the genetic blueprint for people over 80.

Researchers Report:

• Aid recovery during brain injury
• Cognitive clarity for the elderly

Ventfort

The natural version of blood vessel bioregulator peptides. Shown to lower cholesterol and strengthen capillaries in a clinical study of 49 patients.

Researchers Report:

• Improved circulation
• Improved cardiovascular markers on blood tests

Cardiogen

A heart peptide with a unique dual action to help heart muscle cells grow and stop scar tissue formation. It affects over 230 different genes in heart tissue.

Researchers Report:

• Better heart function
• Improved endurance
• Stronger cardiovascular performance

Chelohart

A natural heart peptide that takes longer to kick in but has longer-lasting effects. Many researchers use Cardiogen first and switch to Chelohart for maintenance.

Researchers Report:

• Better heart support
• Better heart-rhythm
• Enhanced stamina

Bonomarlot

This bioregulator peptide acts on bone marrow, where your blood cells are made.

Bone marrow slows down as we age, which can cause anemia, weaker immunity, and slower healing. Bonomarlot is used to support the production.

Clinical studies show it’s effective to treat anemia. People who used it alongside conventional therapy noticed a 24% reduction in recovery time, with significant improvements in erythrocyte (red blood cell) and hemoglobin counts.

Researchers Report:

• More energy
• Faster recovery from illness
• Faster recovery from anemia

Taxorest

A respiratory peptide beneficial for lungs and airways. Limited research, but former smokers and residents of polluted cities report the positive effects.

Researchers Report:

• Easier to breathe
• Fewer respiratory issues

Sigumir

A peptide for cartilage and joints. Common for people with arthritis. It hits the joint tissue rather than just hiding symptoms.

Researchers Report:

• Better joint mobility
• Less stiffness
• Easier to move around

Endoluten

A natural peptide for the pineal gland, like a natural version of Epitalon. Both are designed to counteract age-related decline, enhance sleep, and perhaps even extend lifespan.

Researchers Report:

• Deeper sleep
• Healthier circadian rhythm
• More enduring energy levels

Vladonix

The natural thymus peptide. The natural version of Thymalin.

The effects develop slightly slower but last longer.

Researchers Report:

• Sustained immune support
• Fewer colds and infections
• Better total endurance

Crystagen

A synthetic immune peptide that is faster than the natural options.

Offers a quick immune boost. Some use the drug when they sense a sickness is approaching and then switch over to Vladonix for longer-term help.

Researchers Report:

• Quick immune response
• Faster recovery from sickness

Testoluten

A testicular complex peptide for testosterone that won’t add external hormones but is able to support the body’s own production.

Researchers Report:

• Better energy
• Improved vitality
• Support for reproductive health

Libidon

A type of peptide that aims directly at prostate tissue, instead of treating symptoms.

Researchers say they use it to treat prostate enlargement, chronic prostatitis, erectile dysfunction, and male infertility.

Researchers Report:

• Better prostate function
• Fewer bathroom trips at night
• Improved urinary health

Zhenoluten

Ovary peptide for women that supports natural hormone production. Useful during menopause.

Researchers Report:

• Hormonal balance
• Easier menopausal transition

Suprefort

A pancreatic peptide that facilitates digestive enzymes and insulin secretion.

Researchers Report:

• Better digestion
• Stable blood sugar
• Improved nutrient digestion

Glandokort

Adrenal peptide for stress response that facilitates cortisol regulation without stimulating external hormones.

Researchers Report:

• Better stress management
• Balanced energy throughout the day
• Less burnout

Ovagen

A liver and gut peptide that promotes liver cell regeneration and a healthy gut lining.

Researchers Report:

• Better liver function
• Improved digestion
• Feeling “cleaner” internally

Svetinorm

The natural liver peptide has a slower onset but longer duration.

Researchers  Report:

• Sustained liver support
• Better detox capacity
• Improved energy

Pielotax

A kidney peptide that improved kidney function from Stage 3 chronic kidney disease to near normal in a matter of months.

Researchers Reportg:

• Better kidney markers on tests
• Improved energy
• Less water retention

Chitomur

A peptide that supports bladder wall function and control.

Researchers Report:

• Better bladder control
• Fewer bathroom trips
• Less urgency

Normoftal

A general eye bioregulator peptide that assists with general eye health and function.

Researchers Report:

• Clearer vision
• Less eye strain
• Better visual stamina

Retinalamin

A specific peptide used clinically in Russia for retinal ailments. More targeted than Normoftal.

What users report:

• Support age-related vision changes
• Better night vision
• Sharper visual acuity

Biomarkers to Track

Test before and after to see what changes.

• For Epitalon: Telomere length testing, melatonin levels, and circadian rhythm markers.
• For Thymalin: IgG antibody levels and markers of systemic inflammation.
• For Bonomarlot: Hemoglobin and erythrocyte (red blood cell) counts.
• For kidney peptides: GFR, creatinine, BUN
• For liver peptides: ALT, AST, bilirubin, albumin
• For heart peptides: Lipid panels, CRP
• For immune peptides: Lymphocyte counts, immunoglobulins
• For overall aging: DNA methylation, biological age clocks

Where to Buy Quality Products

The market ships everything from pharmaceutical-grade to complete fakes. You must verify quality. For our clients, we use BioLongevity Labs. We prefer the capsules, though they also offer vials and healing creams.

Green Flags:

• HPLC purity testing (should be 98% or higher)
• Batch-specific certificates of analysis
• Third-party testing from independent labs

Red flags:

• No certificate of analysis
• Prices are way below $40 per bottle
• No third-party testing
• Unclear where it’s made

Storage

Powder peptides:

• Room temperature: 2 to 3 weeks max
• Refrigerator: a few weeks
• Freezer: 1 to 2 years
• Deep freeze: 3+ years

Key rules:

• Keep away from light
• Keep dry
• Don’t freeze and thaw repeatedly
• Never refreeze once mixed

Capsules: Keep at room temperature. Cool and dry.

Mixed peptides: Refrigerate and use within 15 to 25 days.

Legal Status

Russia: Six have approved pharmaceuticals. 64+ are supplements. Available at pharmacies.

United States: Gray area. Not FDA approved, but not banned. Sold as research chemicals or supplements. When injectable peptides were limited, oral bioregulators remained legal.

UK: Research chemicals only.

EU: Research chemicals only. Law enforcement varies from country to country.

The Bottom Line

Bioregulator peptides aren’t like regular peptides.

They don’t force the body into action; they make cells remember to work. Short peptides (2–4 amino acids) such as Vilon and Epitalon are signaling molecules that can be translocated into the cell nucleus and directly interact with DNA.

• Epigenetic Unlock: They bind to special “promoter” sites on genes and interact with histones (H1/3, H1/6).
• Gene Activation: That binds the DNA, loosening this structure, “unfolding” the DNA as the cell turns back on the gene, letting genes that were silenced or “compressed” by age by heterochromatinization.
• Protein Synthesis: After the genes are available for the cell to access, they bring about the synthesis of the tissue-specific proteins required for organ repair or function.

Half a century of research and still going on.

Make sure to be assured that your research chemical is not garbage.